The show itself is a little weird. Basically, a werewolf, a vampire and a ghost end up as roommates. The werewolf (George) and the vampire (Mitchell) had an established friendship before the show begins. Anna the ghost, however, already occupies the house they are going to rent. It is where she died. George and Mitchell also work together at the local hospital. The hospital had an isolation room where George could spend his "time of the month" and, well, we all know why vampires like hospitals. Though Mitchell is more of the 'I don't drink human blood' type of vampire so he tries to keep the blood-sucking type away from the patients.
While I think the show has a good premise and has potential, the first episode had a bit too much information shoved into it. Instead of taking the time to introduce our main characters and their quirks, they felt the need to introduce all of the side characters up-front. For example, Lauren (another vampire) could have waited an episode or two before coming into the fold. I understand why the writers wanted to shove as much information at us as possible. After all, you never really know how long your show will last. But too much information at once isn't good either. Let the story unfold on its own. If the show gets canceled before everything is revealed, then perhaps it wasn't a very good story to begin with. However, I think this IS a good story and could use the sprinkling of information well.